Healing Collagen Medical Device is an advanced, CE-certified, injectable Class III medical product designed to promote musculoskeletal healing by restoring and reinforcing the extracellular matrix (ECM). Composed of high-purity, type I collagen of porcine origin, it acts as a biologically active bioscaffold, supporting tissue repair, regeneration, and mechanical integrity in areas affected by injury, overuse, or degenerative changes.
This innovative solution is engineered for application in orthopaedics, sports medicine, physical rehabilitation, and rheumatology, offering a non-pharmacological, regenerative option for a wide range of conditions.
Healing Collagen Medical Device is based on type I collagen, the most abundant collagen in the human body. It plays a vital role in connective tissue architecture and is a key structural protein found in tendons, ligaments, cartilage, bone, and skin.
The product contains highly purified porcine-derived type I collagen, selected for its strong genetic and structural similarity to human collagen (up to 97% homology). This ensures excellent biocompatibility and extremely low immunogenicity, making it safe for repeated injections in various anatomical regions.
Each 2 mL vial contains 100 µg of purified collagen, sometimes combined with plant-based, mineral, or vitamin components tailored for specific anatomical regions and therapeutic goals.
When injected locally, Healing Collagen functions as a bioscaffold that:
This mechanical and biochemical stimulation helps reactivate the natural healing cascade, stimulating the body’s own fibroblasts to produce new collagen and repair the damaged ECM. By supporting cell polarization and the proper transmission of tensile forces, Healing Collagen restores tissue biomechanics and improves functionality.
Bioscaffold Effect: Collagen deposits locally to reinforce injured tissue and guide cellular repair.
Mechanical Support: Enhances load-bearing properties of weakened or degraded tissue.
Restoration of Anisotropy: Reorients collagen fibers to their natural alignment, critical for tensile strength.
Fibroblast Reactivation: Stimulates cells to synthesize new collagen via integrin-mediated mechanotransduction.
Growth Factor Cascade: Induces release of repair mediators such as TGF-β1, CTGF, and IGF-1.
Healing Collagen is:
It can be used alongside other injectable treatments, medications, or physical modalities without contraindications.
Healing Collagen Medical Device is suitable for a broad spectrum of musculoskeletal and neuromuscular conditions, including:
Among its targeted applications, the use of Healing Collagen for the knee joint stands out for its versatility and proven efficacy. This formulation includes Arnica, a well-known natural anti-inflammatory and analgesic, to enhance joint mobility and reduce pain during movement.
Knee osteoarthritis and related degenerative joint changes often lead to reduced range of motion, swelling, and functional limitations. By reinforcing collagen structure, modulating inflammation, and restoring extracellular matrix integrity, Healing Collagen helps address the root mechanical and biological dysfunctions contributing to joint degradation.
When combined with Arnica:
-The analgesic effect is enhanced
-Post-activity soreness and swelling are reduced
-Patients report improved ease of movement and range of motion
-It serves as a complementary or alternative therapy to corticosteroids or HA injections
The treatment is especially suitable for:
-Mild to moderate knee osteoarthritis
-Post-injury or post-surgical rehabilitation of the knee
-Athletes with chronic knee strain or overuse syndromes
-Patients seeking non-steroidal, regenerative approaches to knee pain management
Healing Collagen for the knee may be administered weekly over 3–5 sessions and can be safely used alongside physiotherapy or rehabilitation programs to accelerate recovery.
Healing Collagen is ideal for:
Healing Collagen is administered via locoregional injection, tailored to the specific needs of the affected tissue. Depending on the anatomical target and condition being treated, injections may be delivered:
Healing Collagen can be safely combined with physical therapy, rehabilitation programs, and other injectables (e.g., hyaluronic acid, PRP) to enhance outcomes. Its versatility makes it suitable for multidisciplinary treatment plans aimed at long-term musculoskeletal recovery.
Numerous clinical studies support the use of injectable collagen for:
In one trial, Healing Collagen performed as well as hyaluronic acid for knee OA, with significant pain reduction and improved mobility maintained over a 6-month follow-up. Other studies showed superior outcomes in muscle pain reduction and enhanced function compared to lidocaine and traditional treatments.
Preclinical studies confirm its role in stimulating tenocyte activity and improving collagen turnover at the cellular level.
Healing Collagen Medical Device offers a regenerative, targeted approach to managing a wide range of musculoskeletal conditions. By restoring the structure and function of connective tissues, it enables real healing, not just temporary relief.
Whether you’re struggling with osteoarthritis, recovering from injury, or managing chronic pain, Healing Collagen provides a natural, scientifically grounded therapy that works with your body to heal and strengthen from within.
Facing persistent knee pain? Take control of your mobility and comfort—schedule your consultation today and begin your journey towards relief with personalized, expert care.